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in 1996. EXTOXNET no longer updates this information, but it may be useful
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EXTOXNET primary files maintained and archived at Oregon State
Revised June 1996
Trade and Other Names:
Trade names for products containing fenoxycarb include Comply,
Insegar, Logic, Pictyl, Torus, and Varikill.
Fenoxycarb is a practically non-toxic pesticide in EPA toxicity
class IV. It is a General Use Pesticide (GUP), and labels for
products containing it must bear the Signal Word CAUTION.
Fenoxycarb is a non-neurotoxic carbamate insect growth regulator
used to control a wide variety of insect pests. It is used as a
fire ant bait and for flea, mosquito, and cockroach control, and
can also be used to control butterflies, moths, beetles, and
scale and sucking insects on olives, vines, cotton, and fruit. It
is also used to control these pests on stored products, and is
often formulated as a grit or corncob bait. Fenoxycarb blocks the
ability of an insect to change into the adult stage from the the
juvenile stage (metamorphosis). It also interferes with larval
molting, the periodic shedding or molting of the old exoskeleton
and production of a new, larger one.
Formulation: It is also
used to control these pests on stored products, and is often
formulated as a grit or corncob bait.
- Acute toxicity: Fenoxycarb is
practically non-toxic to mammals via the oral route. The
oral LD50 of the compound is greater than 10,000 mg/kg in
rats . It is slightly to practically nontoxic via the
dermal route, with a reported dermal LD50 in the rat of
greater than 2000 mg/kg . When 2000 mg/kg were
administered to the animals' skin, rats exhibited labored
breathing, curved body position, and diarrhea, but no
deaths occurred . Fenoxycarb is not a skin sensitizer
in guinea pigs and causes only minimal eye irritation
when applied to rabbits . The inhalation toxicity of
fenoxycarb is moderate, with an acute inhalation LC50 in
rats of greater than 0.480 mg/L .
- Chronic toxicity: Rats fed very low
doses of fenoxycarb for a year had no compound-related
effects at or below the 10 mg/kg/day dose. Dogs fed the
compound at doses of 15.9 mg/kg/day or below for 1 1/2
months experienced no adverse effects . Similar
results were noted for the compound in mice (1.4 mg/kg)
and in rats (0.8 mg/kg/day) over a longer period .
- Reproductive effects: No data are
- Teratogenic effects: With an unknown
species, there were no teratogenic effects observed at
doses of up to 300 mg/kg/day .
- Mutagenic effects: According to the
Environmental Protection Agency, fenoxycarb is not
- Carcinogenic effects: No data are
- Organ toxicity: The liver is the primary
organ affected by fenoxycarb in long-term animal studies
- Fate in humans and animals: About 90% of
a dose of fenoxycarb fed to rats was excreted within 96
hours. No residues were found in the animals' organs
- Effects on birds: Fenoxycarb is
practically nontoxic to birds . The compound has LD50s
greater than 3000 mg/kg and 7000 mg/kg in mallard ducks
and bobwhite quail, respectively [10,36]. The dietary
LC50 value for bobwhite quail is about 11,000 ppm .
- Effects on aquatic organisms: Fenoxycarb
is considered moderately to highly toxic to fish with
LC50s ranging from 1.6 mg/L in rainbow trout to 10.3 mg/L
in carp . Fenoxycarb is also considered highly toxic
to the aquatic invertebrate Daphnia and affects growth
and reproduction after chronic exposures to >1.6 ng/L
. However, when fenoxycarb was applied at rates
ranging from 0.015 to 0.03 lbs/acre to ponds, the
compound had no effect on a number of different
invertebrates including cladocerans, copepods, ostracods,
and mayfly nymphs . In one study, bluegill sunfish
accumulated 20 times the amount of the compound's
concentration in the water. Tissue residues of the
pesticide quickly declined after the fish were placed in
pesticide-free water . Therefore, it is unlikely that
the compound would pose a threat to endangered aquatic
organisms or to other organisms that consumed the fish.
- Effects on other organisms: Fenoxycarb
is practically nontoxic to bees .
- Breakdown in soil and groundwater:
Fenoxycarb is of low persistence in the soil environment,
with a reported field half-life of one day . It is
readily broken down in soil by the chemical action of
water (hydrolysis) and by microbial action. The compound
also has a low potential for leaching from the soil and
has a moderate to strong tendency for soil binding .
These characteristics of fenoxycarb in soil indicate that
it is unlikely to contaminate groundwater.
- Breakdown in water: The compound is
stable to hydrolysis in acidic water. It breaks down very
rapidly in the presence of sunlight (photodegrades) in
water. Half of the initial amount of the compound is
broken down by this means within 5 hours . It readily
attaches onto organic matter which may limit its
persistence in water. Residues in the water could be
detected for only two days following an aerial treatment
of ponds for the control of mosquitoes .
- Breakdown in vegetation: Fenoxycarb is
expected to break down relatively quickly in plants .
- Appearance: Not Available
- Chemical Name: ethyl
- CAS Number: 79127-80-3
- Molecular Weight: 301.30
- Water Solubility: 6 mg/L @ 20 C 
- Solubility in Other Solvents: s. hexane;
v.s. in acetone, chloroform, diethyl ether, and methanol
- Melting Point: 53-54 C 
- Vapor Pressure: 0.0078 mPa @ 20 C 
- Partition Coefficient: 4.3010 
- AdsorptionCoefficient: 1500 
- ADI: Not Available
- MCL: Not Available
- RfD: Not Available
- PEL: Not Available
- HA: Not Available
- TLV: Not Available
P.O. Box 18300
Greensboro, NC 27419-8300
- Phone: 800-334-9481
- Emergency: 800-888-8372
References for the information in this PIP can be found in
Reference List Number 3
information in this profile does not in any way replace or
supersede the information on the pesticide product labeling or
other regulatory requirements. Please refer to the pesticide