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EXTOXNET primary files maintained and archived at Oregon State
Revised June 1996
Trade and Other Names:
Aldicarb is also called aldicarbe. Trade names include Temik, ENT
27093, OMS 771, and UC 21149.
Aldicarb is a Restricted Use Pesticide (RUP) in the U.S. RUPs may
be purchased and used only by certified applicators. Aldicarb is
rated toxicity class I - highly toxic. Products containing
aldicarb bear the signal word DANGER-POISON on the label.
Aldicarb, a member of the carbamate class of chemicals, is an
extremely toxic systemic insecticide. Used to control mites,
nematodes, and aphids, it is applied directly to the soil. It is
used widely on cotton, peanut, and soybean crops. In the
mid-1980s, there were highly publicized incidents in which
misapplication of aldicarb contaminated cucumbers and watermelons
and led to adverse effects in people. In 1990, the manufacturer
of Temik (aldicarb), announced a voluntary halt on its sale for
use on potatoes because of concerns about groundwater
Formulation: It is
formulated as a granular mix (10 to 15% active ingredient)
because of its toxicity. It is not compatible with alkaline
materials and is noncorrosive to metals and plastics.
- Acute toxicity: The primary route of
human exposure to aldicarb is consumption of contaminated
food and of water from contaminated wells .
Occupational exposure to high levels of aldicarb is due
to product handling and most cases of aldicarb poisoning
occur from loading and application of the pesticide.
Atypical of carbamates in general, aldicarb is extremely
toxic through both the oral and dermal routes .
Absorption from the gut is rapid and almost complete.
When administered in oil or other organic solvents
aldicarb is absorbed rapidly through the skin. Its skin
toxicity is roughly 1000 times that of other carbamates
. In humans, the onset of symptoms is rapid, 15
minutes to 3 hours. Symptoms disappear in 4 to 12 hours
. Aldicarb's LD50 in rats, mice, guinea pigs, and
rabbits ranges from 0.5 mg/kg to 1.5 mg/kg when
administered in a liquid or oil form. The toxicities of
the dry granules are distinctly lower (LD50 = 7.0 mg/kg),
though still highly toxic [5,15]. Aldicarb is a
cholinesterase inhibitor and so can result in a variety
of symptoms including weakness, blurred vision, headache,
nausea, tearing, sweating, and tremors. Very high doses
can result in death due to paralysis of the respiratory
- Chronic toxicity: There is very little
evidence of chronic effects from aldicarb exposure. Rats
and dogs fed low doses of aldicarb for two years showed
no significant adverse effects . One epidemiological
study suggested a possible link between low-level
exposure and immunological abnormalities . The
results of this study have been widely disputed.
- Reproductive effects: Aldicarb
administered to pregnant rats at very low levels (0.001
to 0.1 mg/kg/day) depressed acetylcholinesterase activity
more in the fetuses than in the mother. The aldicarb was
also retained in the mother's body for longer periods
than in nonpregnant rats . A three-generation study
at doses of 0.05 and 0.10 mg/kg/day produced no
significant toxic effects and in another study, a dose of
0.70 mg/kg/day produced no adverse effects . Thus,
reproductive effects in humans are unlikely at expected
- Teratogenic effects: No teratogenic
effects have been found in rats exposed to aldicarb .
- Mutagenic effects: Studies show that
aldicarb is not mutagenic .
- Carcinogenic effects: Studies indicate
that aldicarb is not carcinogenic .
- Organ toxicity: Aldicarb's effects are
seen primarily on the nervous system.
- Fate in humans and animals: Aldicarb is
metabolized and quickly excreted. Rats and cows eliminate
80 to 90% of a dose of aldicarb within 24 hours.
Elimination is mainly through urine, but some aldicarb
leaves by way of the lungs in expired air and some
through milk in cows .
- Effects on birds: Aldicarb is very
highly toxic to birds. The greatest exposure to the
organisms is through the ingestion of unincorporated
granules and contaminated earthworms . The LD50s of
the compound range from 1.78 mg/kg in the red-winged
blackbird to 5.34 mg/kg in the ring-necked pheasant.
- Effects on aquatic organisms: Aldicarb
is moderately toxic to fish. The LC50 (96-hour) is 8.8
mg/L in rainbow trout and 1.5 mg/L in bluegill sunfish
. Bioconcentration in aquatic species is low
- Effects on other organisms: Aldicarb is
not toxic to bees, even when applied directly .
- Breakdown in soil and groundwater:
Aldicarb is moderately persistent in soil . Moisture
and pH have important impacts on the rate of breakdown.
Aldicarb is very soluble and mobile in soil . Aldicarb
movement is most serious for sandy or sandy loam soils.
It has been found in wells in over 25 countries and in 12
states at concentrations above the drinking water Maximum
Contaminant Level .
- Breakdown in water: The half-life of
aldicarb in water is from 1 day to a few months . In
pond water, aldicarb is broken down rapidly and has a
half-life of 5 to 10 days. It is degraded by bacteria,
sunlight, and reactions with water. Because of its rapid
degradation rate, levels in surface water may be lower
than those in groundwater .
- Breakdown in vegetation: In plants,
aldicarb is rapidly converted to sulfoxide and more
slowly to the sulfone compound. Citrus trees treated with
18 g per tree had the highest residue levels in the
leaves . Residues of aldicarb also have been reported
in sugar beets and grape leaves and fruit . In 1991,
the manufacturer called for a halt to aldicarb use on
bananas because of the elevated levels of residue found.
- Appearance: Aldicarb is a white
crystalline solid. It is formulated as a granular mix (10
to 15% active ingredient) because of its toxicity. It is
not compatible with alkaline materials and is
noncorrosive to metals and plastics.
- Chemical Name:
- CAS Number: 116-06-3
- Molecular Weight: 190.27
- Water Solubility: 6000 mg/L @ room
- Solubility in Other Solvents: s. in
acetone, xylene, ethyl ether, toluene, and other organic
- Melting Point: 99-100 C 
- Vapor Pressure: 13 mPa @ 20 C 
- Partition Coefficient: 0.0531
- Adsorption Coefficient: 30 
- ADI: 0.003 mg/kg/day 
- MCL: 0.003 m/L 
- RfD: 0.001 mg/kg/day 
- PEL: Not Available
- HA: Not Available
- TLV: Not Available
Rhone-Poulenc Ag. Co.
P.O. Box 12014
2 T.W. Alexander Park, NC 27709
- Phone: 919-549-2000
- Emergency: 800-334-7577
References for the information in this PIP can be found in
Reference List Number 3
information in this profile does not in any way replace or
supersede the information on the pesticide product labeling or
other regulatory requirements. Please refer to the pesticide